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Pangea Systems and Intelligent Medical Objects form Pharmacogenomics Collaboration

04/09/1998

Pangea to Adopt IMO's Medical Lexicon as Standard Descriptive Tool for Medical Information

OAKLAND, California, April 9, 1998 - Pangea Systems®, Inc. and Intelligent Medical Objects, Inc., (IMO) of Chicago, Illinois today announced a three year collaboration aimed at standardizing the way that medical and veterinary information is described and tracked in biopharmaceutical research. The two companies will incorporate IMO's Medical Lexicon into Pangea's information management environment, thus enabling Pangea's customers to use an integrated coding system to collect and annotate the physiological samples employed in their gene expression and pharmacogenomic databases.

The IMO Medical Lexicon integrates and cross-links three coding systems (SNOMED, ICD9, and CPT) that are widely used by physicians, researchers, pathologists, and hospitals to categorize and describe medical information. The IMO Lexicon includes patient symptoms, demographics, disease states, tissue morphology and medical/surgical procedures. Incorporating the IMO Medical Lexicon into Pangea's bioinformatics platform will allow pharmaceutical developers to use the same standard codes in their pre-clinical and genomic research efforts.

"The collaboration with IMO will enable us to tighten the linkage between tissue providers, both human and animal, and Pangea's biopharmaceutical customers who will employ information about those tissues and the individuals from which they came in drug discovery," said Joel Bellenson co-founder of Pangea Systems. "Eventually, we believe this better handling capacity for medical information will be extended to improved disease diagnosis and the fine-tailoring of drug treatments to specific patient needs based on their pharmacogenomic profiles."

"We are very excited about the prospect of the IMO Medical Lexicon becoming a standard for use in the burgeoning field of molecular medicine," said Frank Naeymi-Rad, President of IMO. "Pangea is an ideal partner for us in this effort, due to the company's focus on creating an open, flexible computing environment that can accommodate and integrate a wide variety of genomic and drug-discovery databases and applications."

Intelligent Medical Objects, Inc., (IMO) is a medical software development and knowledge management consulting firm. The IMO core team, consisting of medical doctors, software developers and engineers, is based in Chicago with offices in California and England. ORACLE Corporation has nominated IMO for the Smithsonian Institute's award on using technology for the benefit of humanity. For more information about IMO and IMO's products and consulting services, call 888-IMO-MAIN (466-6246) or visit IMO's web site at http://www.imo-online.com.

Pangea Systems, Inc. is a leader in advanced bioinformatics-the application of information technology to biological research. Pangea Systems' sophisticated, intuitive software applications enhance the ability of pharmaceutical and biotech companies to discover the molecular mechanism of a disease. These applications integrate data with analysis and visualization tools for biological and chemical information, effectively simplifying and accelerating the drug discovery process. Customers selecting Pangea's software solutions are able to transform raw data into valuable information, allowing scientists to focus on biology instead of computer science.

The Company's software applications leverage life science knowledge and employ industrial-strength relational database management systems, a distributed, open architecture and Java-enabled, web-based technologies.

Incorporated in 1993, Pangea Systems, Inc. is a privately held, Oakland, California-based company. For more information, contact Pangea Systems, Inc., at (510) 628-0100, or e-mail us at info-pr@PangeaSystems.com or visit http://www.PangeaSystems.com